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Article

An improved algorithm for inferring mutational parameters from bar-seq evolution experiments.

BMC genomics - 6 May 2023

Li Fangfei, Mahadevan Aditya, Sherlock Gavin

Abstract excerpt

BACKGROUND: Genetic barcoding provides a high-throughput way to simultaneously track the frequencies of large numbers of competing and evolving microbial lineages. However making inferences about the nature of the evolution that is taking place remains a difficult task. RESULTS: Here we describe an algorithm for the inference of fitness effects and establishment times of beneficial mutations from barcode...

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Identifiers

PMID: 37149606
DOI: 10.1186/s12864-023-09345-x
PMCID: PMC10164349

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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