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Article

Understanding the relationship between loneliness, substance use traits and psychiatric disorders: A genetically informed approach.

Psychiatry research - 1 Jul 2023

Martin Ellen, Schoeler Tabea, Pingault Jean-Baptiste, Barkhuizen Wikus

Abstract excerpt

Loneliness is a common, yet distressing experience associated with adverse outcomes including substance use problems and psychiatric disorders. To what extent these associations reflect genetic correlations and causal relationships is currently unclear. We applied Genomic Structural Equation Modelling (GSEM) to dissect the genetic architecture between loneliness and psychiatric-behavioural traits. Included were...

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Identifiers

PMID: 37146462
DOI: 10.1016/j.psychres.2023.115218
PMCID: PMC10636586

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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