Article
Genetic variation in chromatin state across multiple tissues in Drosophila melanogaster.
PLoS genetics - 1 May 2023
Huynh Khoi, Smith Brittny R, Macdonald Stuart J, Long Anthony D
Abstract excerpt
We use ATAC-seq to examine chromatin accessibility for four different tissues in Drosophila melanogaster: adult female brain, ovaries, and both wing and eye-antennal imaginal discs from males. Each tissue is assayed in eight different inbred strain genetic backgrounds, seven associated with a reference quality genome assembly. We develop a method for the quantile normalization of ATAC-seq fragments and test for...
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