Article
Case Report: Molecular autopsy underlie COVID-19-associated sudden, unexplained child mortality.
Frontiers in immunology - 1 Jan 2023
Unuma Kana, Tomomasa Dan, Noma Kosuke, Yamamoto Kouhei, Matsuyama Taka-Aki, Makino Yohsuke, Hijikata Atsushi, Wen Shuheng, Ogata Tsutomu, Okamoto Nobuhiko, Okada Satoshi, Ohashi Kenichi, Uemura Koichi, Kanegane Hirokazu
Abstract excerpt
Herein, we report a child with COVID-19 and seemingly no underlying disease, who died suddenly. The autopsy revealed severe anemia and thrombocytopenia, splenomegaly, hypercytokinemia, and a rare ectopic congenital coronary origin. Immunohistochemical analysis demonstrated that the patient had acute lymphoblastic leukemia of the B-cell precursor phenotype (BCP-ALL). The complex cardiac and hematological...
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