Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Malignant diseases in Noonan syndrome and related disorders.

Hormone research - 1 Dec 2009

Hasle Henrik

Abstract excerpt

The overall risk of cancer in children with Noonan (NS), cardio-facial-cutaneous, Costello or LEOPARD syndrome is high, although no precise estimates are available. There are few data on cancer in adults with NS, but the reported numbers of malignancies in adults do not seem excessive. Juvenile myelomonocytic leukemia (JMML) is a rare aggressive leukemia in young children. A JMML-like myeloproliferative disorder...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Costello Syndrome
Share to LEOPARD Syndrome
Share to Leukemia, Myelomonocytic, Juvenile

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Neuroblastoma

Share to Noonan Syndrome

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to Rhabdomyosarcoma

Share to Urinary Bladder Neoplasms

Source

Identifiers

PMID: 20029231
DOI: 10.1159/000243773

Genes

PTPN11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Malignant diseases in Noonan syndrome and related disorders.PMID 20029231Read ↗

Juvenile myelomonocytic leukaemia and Noonan syndrome.Semantic proximity Read ↗

Cancer in Noonan, Costello, cardiofaciocutaneous and LEOPARD syndromes.Semantic proximity Read ↗

Noonan Syndrome-related Myeloproliferative Disorder Occurring in the Neonatal Period: Case Report and Literature Review.Semantic proximity Read ↗

Noonan syndrome and related disorders: genetics and pathogenesis.Semantic proximity Read ↗

Respiratory failure, juvenile myelomonocytic leukemia, and neonatal Noonan syndrome.Semantic proximity Read ↗

Noonan syndrome.Semantic proximity Read ↗

Noonan syndrome – a new surveySemantic proximity Read ↗

Juvenile myelomonocytic leukemia in a 16-year-old with Noonan syndrome: case report.Semantic proximity Read ↗

Cancer risk in patients with Noonan syndrome carrying a PTPN11 mutation.Semantic proximity Read ↗

Clinical and Genetic Characterization of Noonan Syndrome in a Colombian Pediatric CohortSemantic proximity Read ↗

RAS diseases in children.Semantic proximity Read ↗

Ras/MAPK syndromes and childhood hemato-oncological diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.