Article
Definitive Endodermal Cells Supply an in vitro Source of Mesenchymal Stem/Stromal Cells
1 May 2023
Abstract excerpt
Abstract Mesenchymal stem/Stromal cells (MSCs) have great therapeutic potentials, and they have been isolated from various tissues and organs including definitive endoderm (DE) organs, such as the lung, liver and intestine. MSCs have been induced from human pluripotent stem cells (hPSCs) through multiple embryonic lineages, including the mesoderm, neural crest, and extraembryonic cells. However, it remains...
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