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SUMOylation patterns and signature characterize the tumor microenvironment and predict prognosis in lung adenocarcinoma

13 Apr 2023

Abstract excerpt

Background: Recent studies have revealed that SUMOylation modifications are involved in various biological processes, including cancer development and progression. However, the precise role of SUMOylation in lung adenocarcinoma (LUAD), especially in the tumor immune microenvironment, is not yet clear. Methods: We identified SUMOylation patterns by unsupervised consensus clustering based on the expression of...

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PMID: 37123398
DOI: 10.3389/fcell.2023.1094588

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