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Increased ENT2 expression and its association with altered purine metabolism in cell lines derived from different stages of colorectal cancer

24 Mar 2023

Abstract excerpt

Colorectal cancer (CRC) is one of the most prevalent malignant cancer types worldwide. Although the purine metabolism pathway is vital for cancer cell survival, little is known about the role of equilibrative nucleoside transporter 2 (ENT2) in CRC development and its association with purine metabolites. The aim of the present study was to evaluate the levels of hypoxanthine phosphoribosyl transferase (HPRT),...

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PMID: 37123217
DOI: 10.3892/etm.2023.11911

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