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Exosomal miRNAs in the Tumor Microenvironment of Multiple Myeloma

28 Mar 2023

Abstract excerpt

Multiple myeloma (MM) is a malignancy of plasma cells in the bone marrow and is characterized by the clonal proliferation of B-cells producing defective monoclonal immunoglobulins. Despite the latest developments in treatment, drug resistance remains one of the major challenges in the therapy of MM. The crosstalk between MM cells and other components within the bone marrow microenvironment (BME) is the major...

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PMID: 37048103
DOI: 10.3390/cells12071030

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