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MicroRNAs and exosomes: Small molecules with big actions in multiple myeloma pathogenesis

11 Dec 2019

Abstract excerpt

Multiple myeloma (MM), an incurable hematologic malignancy of plasma cells increasing in the bone marrow (BM), has a complex microenvironment made to support proliferation, survival, and drug resistance of tumor cells. MicroRNAs (miRNAs), short non-coding RNAs regulating genes expression at posttranscriptional level, have been indicated to be functionally deregulated or abnormally expressed in MM cells. Moreover,...

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PMID: 31828868
DOI: 10.1002/iub.2211

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