Article
Analysis of Amount, Size, Protein Phenotype and Molecular Content of Circulating Extracellular Vesicles Identifies New Biomarkers in Multiple Myeloma.
International journal of nanomedicine - 1 Jan 2021
Laurenzana Ilaria, Trino Stefania, Lamorte Daniela, Girasole Marco, Dinarelli Simone, De Stradis Angelo, Grieco Vitina, Maietti Maddalena, Traficante Antonio, Statuto Teodora, Villani Oreste, Musto Pellegrino, Sgambato Alessandro, De Luca Luciana, Caivano Antonella
Abstract excerpt
INTRODUCTION: Extracellular vesicles (EVs) are naturally secreted cellular lipid bilayer particles, which carry a selected molecular content. Owing to their systemic availability and their role in tumor pathogenesis, circulating EVs (cEVs) can be a valuable source of new biomarkers useful for tumor diagnosis, prognostication and monitoring. However, a precise approach for isolation and characterization of cEVs as...
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