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Article

Genetic loci of beta-aminoisobutyric acid are associated with aging-related mild cognitive impairment.

Translational psychiatry - 29 Apr 2023

Granot-Hershkovitz Einat, Spitzer Brian, Yang Yunju, Tarraf Wassim, Yu Bing, Boerwinkle Eric, Fornage Myriam, Mosley Thomas H, DeCarli Charles, Kristal Bruce S, González Hector M, Sofer Tamar

Abstract excerpt

We studied the genetic associations of a previously developed Metabolomic Risk Score (MRS) for Mild Cognitive Impairment (MCI) and beta-aminoisobutyric acid metabolite (BAIBA)-the metabolite highlighted by results from a genome-wide association study (GWAS) of the MCI-MRS, and assessed their association with MCI in datasets of diverse race/ethnicities. We first performed a GWAS for the MCI-MRS and BAIBA, in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37120436
DOI: 10.1038/s41398-023-02437-y
PMCID: PMC10148805

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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