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Article

Association of Methylenetetrahydrofolate Reductase C677T Gene Polymorphisms with Mild Cognitive Impairment Susceptibility: A Systematic Review and Meta-Analysis.

Behavioural neurology - 1 Jan 2021

Sun Jiahui, Jiang Xuefan, Zhao Ming, Ma Lina, Pei Hui, Liu Nanyang, Li Hao

Abstract excerpt

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) C677T (rs1801133) gene polymorphisms are related to a growing risk of Alzheimer's disease; however, whether this association applies to mild cognitive impairment (MCI) remains unclear. OBJECTIVE: We conducted this meta-analysis to evaluate the contribution of MTHFR C677T (rs1801133) gene variants to the risk of MCI. METHODS: PubMed, Embase, Web of Science,...

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Source

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Identifiers

PMID: 34580600
DOI: 10.1155/2021/2962792
PMCID: PMC8464412

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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