Article
Mutational landscape of primary spinal cord astrocytoma.
The Journal of pathology - 1 Jul 2023
Cheng Lei, Zhang Fan, Zhao Xingang, Wang Leiming, Duan Wanru, Guan Jian, Wang Kai, Liu Zhenlei, Wang Xingwen, Wang Zuowei, Wu Hao, Chen Zan, Teng Lianghong, Li Yifei, Xiao Fei, Fan Tao, Jian Fengzeng
Abstract excerpt
Primary spinal cord astrocytoma (SCA) is a rare disease. Knowledge about the molecular profiles of SCAs mostly comes from intracranial glioma; the pattern of genetic alterations of SCAs is not well understood. Herein, we describe genome-sequencing analyses of primary SCAs, aiming to characterize the mutational landscape of primary SCAs. We utilized whole exome sequencing (WES) to analyze somatic nucleotide...
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