Article
Kidney and urinary tract involvement in systemic mastocytosis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 31 Oct 2023
Bharati Joyita, Shah Nikita, Desai Ankuri, Gladstone Douglas, Krushna Das Chandan, Nieto Maria Jacqueline, Jhaveri Kenar D, Izzedine Hassan
Abstract excerpt
Systemic mastocytosis (SM) is a disorder of excessive mast cell accumulation in tissues due to a somatic gain-of-function mutation, commonly in the KIT gene, which prevents apoptosis of mast cells. Whereas bone marrow, skin, lymph nodes, spleen and gastrointestinal tract are commonly involved, kidneys are rarely involved directly by SM. However, there are increasing reports of indirect kidney involvement in...
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