Article
SNP in PTPN22, PADI4, and STAT4 but Not TRAF1 and CD40 Increase the Risk of Rheumatoid Arthritis in Polish Population.
International journal of molecular sciences - 20 Apr 2023
Budlewski Tomasz, Sarnik Joanna, Galita Grzegorz, Dragan Grzegorz, Brzezińska Olga, Popławska Marta, Popławski Tomasz, Makowska Joanna
Abstract excerpt
Single nucleotide polymorphisms in non-HLA genes are involved in the development of rheumatoid arthritis (RA). SNPS in genes: PADI4 (rs2240340), STAT4 (rs7574865), CD40 (rs4810485), PTPN22 (rs2476601), and TRAF1 (rs3761847) have been described as risk factors for the development of autoimmune diseases, including RA. This study aimed to assess the prevalence of polymorphisms of these genes in the Polish population...
