Article
[Correlation between ARID5B Gene SNP and MTX Resistance in Children with ALL].
Zhongguo shi yan xue ye xue za zhi - 1 Apr 2023
Zhang Li-Fen, Ma Yu, Li Lian, Liu Wen-E, Zhang Xiao-Chun
Abstract excerpt
OBJECTIVE: To investigate the correlation between single-nucleotide polymorphism (SNP) of ARID5B gene and resistance to methotrexate (MTX) in children with acute lymphoblastic leukemia (ALL). METHODS: A total of 144 children with ALL who were treated in General Hospital of Ningxia Medical University from January 2015 to November 2021 were enrolled and divided into MTX resistant group and non-MTX resistant group,...
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