Article
Increase in Frequency of Myeloid-Derived Suppressor Cells in the Bone Marrow of Myeloproliferative Neoplasm: Potential Implications in Myelofibrosis.
Advances in experimental medicine and biology - 1 Jan 2023
Kapor Sunčica, Momčilović Sanja, Kapor Slobodan, Mojsilović Slavko, Radojković Milica, Apostolović Milica, Filipović Branka, Gotić Mirjana, Čokić Vladan, Santibanez Juan F
Abstract excerpt
The Philadelphia-negative myeloproliferative neoplasms (MPNs), defined as clonal disorders of the hematopoietic stem cells, are characterized by the proliferation of mature myeloid cells in the bone marrow and a chronic inflammatory status impacting the initiation, progression, and symptomatology of the malignancies. There are three main entities defined as essential thrombocythemia (ET), polycythemia vera (PV),...
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