Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Implications of Tau Dysregulation in Huntington’s Disease and Potential for New Therapeutics

18 Apr 2023

Abstract excerpt

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder. The disease, characterized by motor, cognitive, and psychiatric impairments, is caused by the expansion of a CAG repeat in the huntingtin gene. Despite the discovery of the mutation in 1993, no disease-modifying treatments are yet available. Understanding the molecular and cellular mechanisms involved in HD is therefore crucial for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Neurodegenerative Diseases
Share to Mitochondrial Function and Pathology
Share to Neurological disorders and treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37092231
DOI: 10.3233/jhd-230569

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Implications of Tau Dysregulation in Huntington’s Disease and Potential for New TherapeuticsPMID 37092231Read ↗

Huntington’s Disease: From Genetics to TherapeuticsSemantic proximity Read ↗

The role of tau in the pathological process and clinical expression of Huntington's disease.Semantic proximity Read ↗

Molecular Pathogenesis in Huntington’s DiseaseSemantic proximity Read ↗

Huntington's disease: the coming of age.Semantic proximity Read ↗

Tau protein as a differential biomarker of tauopathies.Semantic proximity Read ↗

How Do Post-Translational Modifications Influence the Pathomechanistic Landscape of Huntington's Disease? A Comprehensive Review.Semantic proximity Read ↗

Huntington’s disease and striatal signalingSemantic proximity Read ↗

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work.Semantic proximity Read ↗

A Review On Huntington Protein: Insight Into Protein Aggregation and Therapeutic Interventions.Semantic proximity Read ↗

Kinases and Their Potential as Therapeutic Targets in Huntington’s DiseaseSemantic proximity Read ↗

Tau and tauopathies.Semantic proximity Read ↗

[Tauopathies : From molecule to therapy].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.