Article
Assessing causal associations of obesity and diabetes with kidney stones using Mendelian randomization analysis.
Molecular genetics and metabolism - 1 Jan 2000
Yuan Shuai, Larsson Susanna C
Abstract excerpt
BACKGROUND: Obesity and type 2 diabetes have been associated with an increased risk of kidney stones in observational studies, but the causality of these associations remains unestablished. We conducted a Mendelian randomization study to determine these associations. METHODS: Independent single nucleotide polymorphisms at the genome-wide significance threshold (p < 5 × 10-8) were selected as instrumental...
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