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Article

Relationships between hourly cognitive variability and risk of Alzheimer's disease revealed with mixed-effects location scale models.

Neuropsychology - 1 Jan 2024

Aschenbrenner Andrew J, Hassenstab Jason, Morris John C, Cruchaga Carlos, Jackson Joshua J

Abstract excerpt

OBJECTIVE: Observational studies on aging and Alzheimer's disease (AD) typically focus on mean-level changes in cognitive performance over relatively long periods of time (years or decades). Additionally, some studies have examined how trial-level fluctuations in speeded reaction time are related to both age and AD. The aim of the current project was to describe patterns of variability across repeated days of...

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PMID: 37079810
DOI: 10.1037/neu0000905
PMCID: PMC10587364

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