Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nonmuscle Myosin IIA Regulates the Precise Alignment of Hexagonal Eye Lens Epithelial Cells During Fiber Cell Formation and Differentiation.

Investigative ophthalmology & visual science - 3 Apr 2023

Islam Sadia T, Cheng Catherine, Parreno Justin, Fowler Velia M

Abstract excerpt

Purpose: Epithelial cells in the equatorial region of the ocular lens undergo a remarkable transition from randomly packed cells into precisely aligned and hexagon-shaped cells organized into meridional rows. We investigated the function of nonmuscle myosin IIA (encoded by Myh9) in regulating equatorial epithelial cell alignment to form meridional rows during secondary fiber cell morphogenesis. Methods: We used...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Epithelial Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lens, Crystalline

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 37070941
DOI: 10.1167/iovs.64.4.20
PMCID: PMC10123325

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nonmuscle Myosin IIA Regulates the Precise Alignment of Hexagonal Eye Lens Epithelial Cells During Fiber Cell Formation and Differentiation.PMID 37070941Read ↗

Disease-related non-muscle myosin IIA D1424N rod domain mutation, but not R702C motor domain mutation, disrupts mouse ocular lens fiber cell alignment and hexagonal packing.Semantic proximity Read ↗

Nonmuscle myosin IIA (NMIIA) regulates anisotropic cell tension to maintain the hexagonal packing of mouse lens meridional row cells.Semantic proximity Read ↗

Multiscale analysis of single and double maternal-zygotic Myh9 and Myh10 mutants during mouse preimplantation development.Semantic proximity Read ↗

The pulling, pushing and fusing of lens fibers: a role for Rho GTPases.Semantic proximity Read ↗

Rod mutations associated with MYH9-related disorders disrupt nonmuscle myosin-IIA assembly.Semantic proximity Read ↗

Nonmuscle Myosin II Regulates the Morphogenesis of Metanephric Mesenchyme–Derived Immature NephronsSemantic proximity Read ↗

Drosophila Myosin II, Zipper, is essential for ommatidial rotation.Semantic proximity Read ↗

Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function.Semantic proximity Read ↗

Tropomodulin 1 Regulation of Actin Is Required for the Formation of Large Paddle Protrusions Between Mature Lens Fiber Cells.Semantic proximity Read ↗

Cos2/Kif7 and Osm-3/Kif17 regulate onset of outer segment development in zebrafish photoreceptors through distinct mechanisms.Semantic proximity Read ↗

Resisting the effects of aging: a function for the fiber cell beaded filament.Semantic proximity Read ↗

Assembly of thick filaments and myofibrils occurs in the absence of the myosin head.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.