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Article

Variation in the BDNF gene interacts with age to predict mortality in a prospective, longitudinal cohort with severe TBI.

Neurorehabilitation and neural repair - 1 Jan 2000

Failla Michelle D, Kumar Raj G, Peitzman Andrew B, Conley Yvette P, Ferrell Robert E, Wagner Amy K

Abstract excerpt

BACKGROUND: Mortality predictions following traumatic brain injury (TBI), and our understanding of TBI pathology, may be improved by including genetic risk in addition to traditional prognostic variables. One promising target is the gene coding for brain-derived neurotrophic factor (BDNF), a ubiquitous neurotrophin important for neuronal survival and neurogenesis. OBJECTIVE: We hypothesized the addition of BDNF...

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Identifiers

PMID: 25063686
DOI: 10.1177/1545968314542617
PMCID: PMC4305354

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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