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Article

A Systematic Comparison of Traditional and Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Genes in More Than 1000 Patients.

The Journal of molecular diagnostics : JMD - 1 Sept 2015

Lincoln Stephen E, Kobayashi Yuya, Anderson Michael J, Yang Shan, Desmond Andrea J, Mills Meredith A, Nilsen Geoffrey B, Jacobs Kevin B, Monzon Federico A, Kurian Allison W, Ford James M, Ellisen Leif W

Abstract excerpt

Gene panels for hereditary breast and ovarian cancer risk assessment are gaining acceptance, even though the clinical utility of these panels is not yet fully defined. Technical questions remain, however, about the performance and clinical interpretation of gene panels in comparison with traditional tests. We tested 1105 individuals using a 29-gene next-generation sequencing panel and observed 100% analytical...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26207792
DOI: 10.1016/j.jmoldx.2015.04.009

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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