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Tailoring baker's yeast Saccharomyces cerevisiae for functional testing of channelrhodopsin.

PloS one - 1 Jan 2023

Höler Sebastian, Degreif Daniel, Stix Florentine, Yang Shang, Gao Shiqiang, Nagel Georg, Moroni Anna, Thiel Gerhard, Bertl Adam, Rauh Oliver

Abstract excerpt

Channelrhodopsin 2 (ChR2) and its variants are the most frequent tools for remote manipulation of electrical properties in cells via light. Ongoing attempts try to enlarge their functional spectrum with respect to ion selectivity, light sensitivity and protein trafficking by mutations, protein engineering and environmental mining of ChR2 variants. A shortcoming in the required functional testing of large numbers...

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PMID: 37053213
DOI: 10.1371/journal.pone.0280711
PMCID: PMC10101416

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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