TUBectomy with delayed oophorectomy as an alternative to risk-reducing salpingo-oophorectomy in high-risk women to assess the safety of prevention: the TUBA-WISP II study protocol.

doi:10.1136/ijgc-2023-004377

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Article

TUBectomy with delayed oophorectomy as an alternative to risk-reducing salpingo-oophorectomy in high-risk women to assess the safety of prevention: the TUBA-WISP II study protocol.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 5 Jun 2023

Steenbeek Miranda P, van Bommel Majke H D, intHout Joanna, Peterson Christine B, Simons Michiel, Roes Kit C B, Kets Marleen, Norquist Barbara M, Swisher Elizabeth M, Hermens Rosella P M G, Lu Karen H, de Hullu Joanne A

Abstract excerpt

BACKGROUND: Risk-reducing salpingectomy with delayed oophorectomy has gained interest for individuals at high risk for tubo-ovarian cancer as there is compelling evidence that especially high-grade serous carcinoma originates in the fallopian tubes. Two studies have demonstrated a positive effect of salpingectomy on menopause-related quality of life and sexual health compared with standard risk-reducing...

Topics

Humans
Female
Adult
Middle Aged
Child, Preschool
Salpingo-oophorectomy
Prospective Studies
Quality of Life
Genes, BRCA1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Ovariectomy

Salpingectomy

BRCA1 Protein

Ovarian Neoplasms

Genetic Predisposition to Disease

Source

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Identifiers

PMID: 37045546
DOI: 10.1136/ijgc-2023-004377
PMCID: PMC10314019

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