Article
Opportunistic salpingectomies for the prevention of a high-grade serous carcinoma: a statement by the Kommission Ovar of the AGO.
Archives of gynecology and obstetrics - 1 Jul 2015
Pölcher Martin, Hauptmann Steffen, Fotopoulou Christina, Schmalfeldt Barbara, Meinhold-Heerlein Ivo, Mustea Alexander, Runnebaum Ingo, Sehouli Jalid
Abstract excerpt
The detection of premalignant cells in the epithelium of the fallopian tube has resulted in revolutionary theories regarding the origin of epithelial ovarian cancer (EOC). Serous tubal intra-epithelial carcinomas (STIC) have been detected in patients with BRCA 1 or 2 mutations and are considered as the most likely precursors of the high-grade serous ovarian cancer (HGSOC), which is the most common histological...
Topics
- Adult
- Carcinoma in Situ
- Carcinoma, Ovarian Epithelial
- Cystadenocarcinoma, Serous
- Epithelium
- Fallopian Tube Neoplasms
- Fallopian Tubes
- Female
- Humans
- Middle Aged
