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Article

Natural genetic variation in a dopamine receptor is associated with variation in female fertility in Drosophila melanogaster.

Proceedings. Biological sciences - 12 Apr 2023

Lyman Richard F, Lyman Rachel A, Yamamoto Akihiko, Huang Wen, Harbison Susan T, Zhou Shanshan, Anholt Robert R H, Mackay Trudy F C

Abstract excerpt

Fertility is a major component of fitness but its genetic architecture remains poorly understood. Using a full diallel cross of 50 Drosophila Genetic Reference Panel inbred lines with whole genome sequences, we found substantial genetic variation in fertility largely attributable to females. We mapped genes associated with variation in female fertility by genome-wide association analysis of common variants in the...

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Identifiers

PMID: 37040806
DOI: 10.1098/rspb.2023.0375
PMCID: PMC10089713

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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