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Article

Lipocalin 2 - mutation screen and serum levels in patients with anorexia nervosa or obesity and in lean individuals.

Frontiers in endocrinology - 1 Jan 2023

Zheng Yiran, Rajcsanyi Luisa Sophie, Kowalczyk Manuela, Giuranna Johanna, Herpertz-Dahlmann Beate, Seitz Jochen, de Zwaan Martina, Herzog Wolfgang, Ehrlich Stefan, Zipfel Stephan, Giel Katrin, Egberts Karin, Burghardt Roland, Föcker Manuel, Al-Lahham Saad, Hebebrand Johannes, Fuhrer Dagmar, Tan Susanne, Zwanziger Denise, Peters Triinu, Hinney Anke

Abstract excerpt

Context: The bone-derived adipokine lipocalin-2 is relevant for body weight regulation by stimulating the leptin-melanocortin pathway. Objective: We aimed to (i) detect variants in the lipocalin-2 gene (LCN2) which are relevant for body weight regulation and/or anorexia nervosa (AN); (ii) describe and characterize the impact of LCN2 and MC4R variants on circulating lipocalin-2 level. Methods: Sanger sequencing of...

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Identifiers

PMID: 37025415
DOI: 10.3389/fendo.2023.1137308
PMCID: PMC10071025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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