Article
Kidney function may partially mediated the protective effect of urinary uromodulin on kidney stone.
Urolithiasis - 6 Apr 2023
Jian Zhongyu, Yuan Chi, Xiong Zheyu, Li Hong, Jin Xi, Wang Kunjie
Abstract excerpt
The causal links between urinary uromodulin (uUMOD) and kidney stone disease (KSD) are still not clarified in general population. We assessed their relationships combining 2-sample Mendelian randomization (MR) and multivariable (MVMR) designs among general population of European ancestry. The summary information for uUMOD indexed to creatinine levels (29,315 individuals) and KSD (395,044 individuals) were from 2...
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