Dermatomyositis With or Without Anti-Melanoma Differentiation-Associated Gene 5 Antibodies: Common Interferon Signature but Distinct NOS2 Expression.

doi:10.1016/j.ajpath.2015.11.010

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Article

Dermatomyositis With or Without Anti-Melanoma Differentiation-Associated Gene 5 Antibodies: Common Interferon Signature but Distinct NOS2 Expression.

The American journal of pathology - 1 Mar 2016

Allenbach Yves, Leroux Gaëlle, Suárez-Calvet Xavier, Preusse Corinna, Gallardo Eduard, Hervier Baptiste, Rigolet Aude, Hie Miguel, Pehl Debora, Limal Nicolas, Hufnagl Peter, Zerbe Norman, Meyer Alain, Aouizerate Jessie, Uzunhan Yurdagul, Maisonobe Thierry, Goebel Hans-Hilmar, Benveniste Olivier, Stenzel Werner

Abstract excerpt

The anti-melanoma differentiation-associated gene 5 (MDA5) autoantibody is specifically associated with dermatomyositis (DM). Nevertheless, anti-MDA5(+)-patients experience characteristic symptoms distinct from classic DM, including severe signs of extramuscular involvement; however, the clinical signs of myopathy are mild or even absent. The morphological and immunological features are not yet described in...

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PMID: 26806087
DOI: 10.1016/j.ajpath.2015.11.010

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NOS2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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