Article
The study of rs324420 (C385A) polymorphism of the FAAH gene of the endocannabinoid system in patients with epilepsy and ADHD.
Epilepsy research - 1 May 2023
Anvar Leila Hosseinzadeh, Alejafar Asghar, Moosavi Seyyed Ebrahim, Charsouei Saeid, Zeynalzadeh Narges, Fanid Leila Mehdizadeh, Emamalizadeh Babak, Aydinlou Zahra Hassanpour, Vaezi Helaleh, Kashefi Adel, Tomaz Carlos, Nikanfar Masoud, Ahmadalipour Ali
Abstract excerpt
The endocannabinoid (eCB) system regulates many physiological functions in the central nervous system. Fatty acid amide hydrolase (FAAH) is an essential enzyme in the eCB system, degrading anandamide. Single nucleotide polymorphism (SNP) rs324420 is a common genetic polymorphism of the FAAH gene and has been associated with susceptibility to neurological conditions. This study examined whether the SNP rs324420...
Read the complete abstract on PubMed