Article
The PPARGC1A Gly482Ser polymorphism is associated with elite long-distance running performance.
Journal of sports sciences - 1 Jan 2023
Hall Elliott C R, Lockey Sarah J, Heffernan Shane M, Herbert Adam J, Stebbings Georgina K, Day Stephen H, Collins Malcolm, Pitsiladis Yannis P, Erskine Robert M, Williams Alun G
Abstract excerpt
Success in long-distance running relies on multiple factors including oxygen utilisation and lactate metabolism, and genetic associations with athlete status suggest elite competitors are heritably predisposed to superior performance. The Gly allele of the PPARGC1A Gly482Ser rs8192678 polymorphism has been associated with endurance athlete status and favourable aerobic training adaptations. However, the...
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