Article
The combined impact of metabolic gene polymorphisms on elite endurance athlete status and related phenotypes.
Human genetics - 1 Dec 2009
Ahmetov Ildus I, Williams Alun G, Popov Daniil V, Lyubaeva Ekaterina V, Hakimullina Albina M, Fedotovskaya Olga N, Mozhayskaya Irina A, Vinogradova Olga L, Astratenkova Irina V, Montgomery Hugh E, Rogozkin Viktor A
Abstract excerpt
Endurance performance is a complex phenotype subject to the influence of both environmental and genetic factors. Although the last decade has seen a variety of specific genetic factors proposed, many in metabolic pathways, each is likely to make a limited contribution to an 'elite' phenotype: it seems more likely that such status depends on the simultaneous presence of multiple such variants. The aim of the study...
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