Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pan‐cancer analysis: SPAG5 is an immunological and prognostic biomarker for multiple cancers

31 Aug 2023

Abstract excerpt

Sperm-associated antigen 5 (SPAG5) is a mitotic spindle protein that regulates the separation of sister chromatids into daughter cells. Recent studies have discovered its overexpression in various cancers, suggesting its oncogenic characteristics and functions. However, a comprehensive analysis of SPAG5 regarding its diagnostic, prognostic, and immune-related effects across different cancer types is lacking. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Ferroptosis and cancer prognosis
Share to Immunotherapy and Immune Responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37650687
DOI: 10.1096/fj.202300626r

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pan‐cancer analysis: SPAG5 is an immunological and prognostic biomarker for multiple cancersPMID 37650687Read ↗

SPAG5 Expression Correlated With Prognostic Implication and Immune Infiltration in Lung AdenocarcinomaSemantic proximity Read ↗

SPAG5 Activates PI3K/AKT Pathway and Promotes the Tumor Progression and Chemo-Resistance in Gastric CancerSemantic proximity Read ↗

High SPAG5 Expression Is Associated With Oncological Features in Endometrial CarcinomaSemantic proximity Read ↗

Comprehensive pan-cancer analysis reveals the importance of SPATS2 in the development of hepatocellular carcinomaSemantic proximity Read ↗

Comprehensive pan-cancer analysis reveals NUSAP1 is a novel predictive biomarker for prognosis and immunotherapy responseSemantic proximity Read ↗

Targeting of mutant-p53 and MYC as a novel strategy to inhibit oncogenic SPAG5 activity in triple negative breast cancer.Semantic proximity Read ↗

BIRC5 is a prognostic biomarker associated with tumor immune cell infiltrationSemantic proximity Read ↗

Spindle component 25 predicts the prognosis and the immunotherapy response of cancers: a pan-cancer analysisSemantic proximity Read ↗

SPAG5 Promotes the Proliferation, Migration, Invasion, and Epithelial-Mesenchymal Transformation of Colorectal Cancer Cells by Activating the PI3K/AKT Signaling PathwaySemantic proximity Read ↗

Pan-Cancer Analysis of PIMREG as a Biomarker for the Prognostic and Immunological RoleSemantic proximity Read ↗

SPATS2 is correlated with cell cycle progression and immune cells infiltration in hepatocellular carcinomaSemantic proximity Read ↗

The Emerging Role of Sperm-Associated Antigen 6 Gene in the Microtubule Function of Cells and CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.