Article
Variant RHD alleles and Rh immunization in patients with sickle cell disease.
British journal of haematology - 1 Jun 2023
Takasaki Kaoru, Friedman David F, Uter Stacey, Vege Sunitha, Westhoff Connie M, Chou Stella T
Abstract excerpt
RH diversity among patients and donors contributes to Rh immunization despite serologic Rh-matched red cell transfusions. Anti-D can occur in D+ patients with RHD variants that encode partial D antigens. Anti-D has also been reported in patients with conventional RHD transfused primarily with units from Black donors who frequently have variant RHD. We report 48 anti-D in 690 D+ transfused individuals with sickle...
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