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Polymorphism of MMP-3 Gene and Imbalance Expression of MMP-3 / TIMP-1 in Articular Cartilage Are Associated With an Endemic Osteochondropathy, Kashin- Beck Disease

2021-04-21

Abstract excerpt

<h4>Background: </h4> The etiology of Kashin-Beck disease (KBD), an endemic osteochondropathy, is largely unknown. Matrix metalloproteinase-3 (MMP-3) plays a central role in the initiation and progression of cartilage destruction, however，no study has reported on the relationship between KBD and MMP-3. The objective of this study was to explore the polymorphism of MMP-3 gene and expression of MMP-3 / TIMP-1(Tissue...

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Literature Corpus work
4292f54a-94e0-5342-97ca-246bdca68667
DOI
10.21203/rs.3.rs-360486/v1
Open publication

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Polymorphism of MMP-3 Gene and Imbalance Expression of MMP-3 / TIMP-1 in Articular Cartilage Are Associated With an Endemic Osteochondropathy, Kashin- Beck DiseaseDOI 10.21203/rs.3.rs-360486/v1
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