Article
Cancer-associated fibroblasts promote malignant phenotypes of prostate cancer cells via autophagy : Cancer-associated fibroblasts promote prostate cancer development.
Apoptosis : an international journal on programmed cell death - 1 Jun 2023
Liu XuKai, Tang JiZu, Peng LiQiang, Nie HaiBo, Zhang YuanGuang, Liu Pan
Abstract excerpt
Dysregulation of autophagy in cancer-associated fibroblasts (CAFs) has been demonstrated to play a role in malignant phenotypes of human tumors. We intended to investigate the function of CAFs autophagy in prostate cancer (PCa). Firstly, CAFs and normal fibroblasts (NFs) were isolated from cancerous and adjacent normal tissues of PCa patients, for the following experimental preparation. In comparison with NFs,...
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