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MAPK signaling pathway-based glioma subtypes, machine-learning risk model, and key hub proteins identification

4 Nov 2023

Abstract excerpt

An early diagnosis and precise prognosis are critical for the treatment of glioma. The mitogen‑activated protein kinase (MAPK) signaling pathway potentially affects glioma, but the exploration of the clinical values of the pathway remains lacking. We accessed data from TCGA, GTEx, CGGA, etc. Up-regulated MAPK signaling pathway genes in glioma were identified and used to cluster the glioma subtypes using consensus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37925483
DOI: 10.1038/s41598-023-45774-0

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