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Article

MFAP4 is a novel prognostic biomarker in glioma correlating with immunotherapy resistance and ferroptosis

21 Feb 2025

Abstract excerpt

Background: Glioma, an aggressive brain tumor, poses a challenge in understanding the mechanisms of treatment resistance, despite promising results from immunotherapy. Methods: Genes associated with immunotherapy resistance were identified by analyzing The Cancer Genome Atlas (TCGA), the Chinese Glioma Genome Atlas (CGGA), and the Gene Expression Omnibus (GEO) database. In addition, gene set enrichment analysis...

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PMID: 40061958
DOI: 10.3389/fphar.2025.1551863

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