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Article

Gut microbiota manipulation during the prepubertal period shapes behavioral abnormalities in a mouse neurodevelopmental disorder model.

Scientific reports - 13 Mar 2020

Saunders Justin M, Moreno José L, Ibi Daisuke, Sikaroodi Masoumeh, Kang Dae Joong, Muñoz-Moreno Raquel, Dalmet Swati S, García-Sastre Adolfo, Gillevet Patrick M, Dozmorov Mikhail G, Bajaj Jasmohan S, González-Maeso Javier

Abstract excerpt

Previous studies demonstrate an association between activation of the maternal immune system during pregnancy and increased risk of neurodevelopmental psychiatric conditions, such as schizophrenia and autism, in the offspring. Relatively recent findings also suggest that the gut microbiota plays an important role in shaping brain development and behavior. Here we show that maternal immune activation (MIA)...

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Identifiers

PMID: 32170216
DOI: 10.1038/s41598-020-61635-6
PMCID: PMC7070045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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