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Peripheral serotonin: cultivating companionship with gut microbiota in intestinal homeostasis

27 Jun 2022

Abstract excerpt

Serotonin, also known as 5-hydroxytryptamine (5-HT), is an evolutionarily ancient and phylogenetically conserved monoamine that regulates multifaceted physiological functions in mammals. 5-HT was, at one time, most extensively studied as a neurotransmitter within the central nervous system but is now known to regulate nonneuronal functions including immune responses in an autocrine-paracrine-endocrine manner....

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PMID: 35759441
DOI: 10.1152/ajpcell.00433.2021

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