Article
Association of an ADRB3 Variant with Coronary Artery Disease Within the Chinese Han Population: Construction of a Predictive Nomogram Model.
Genetic testing and molecular biomarkers - 1 Mar 2023
Zhang Jin-Yu, Zhao Qian, Li Xiao-Mei, Liu Fen, Zhao Qiang, Men Li, Chen Qing-Jie, Zhai Hui, Yang Yi-Ning
Abstract excerpt
Objective: Coronary artery disease (CAD) is a the most common type of heart disease, and is associated with the highest mortality rate. The role of the β3-adrenergic receptor gene (ADRB3) in energy homeostasis and lipolysis suggests that it may be associated with obesity, insulin resistance, diabetes, and hypertension. Herein, we sought to examine the relationship between CAD and variants of the ADRB3 gene in...
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