Article
Systematically identifying genetic signatures including novel SNP-clusters, nonsense variants, frame-shift INDELs, and long STR expansions that potentially link to unknown phenotypes existing in dog breeds.
BMC genomics - 5 Jun 2023
Li Zicheng, Wang Zuoheng, Chen Zhiyuan, Voegeli Heidi, Lichtman Judith H, Smith Peter, Liu Ju, DeWan Andrew T, Hoh Josephine
Abstract excerpt
BACKGROUND: In light of previous studies that profiled breed-specific traits or used genome-wide association studies to refine loci associated with characteristic morphological features in dogs, the field has gained tremendous genetic insights for known dog traits observed among breeds. Here we aim to address the question from a reserve perspective: whether there are breed-specific genotypes that may underlie...
Topics
- Humans
- Dogs
- Animals
- Polymorphism, Single Nucleotide
- Genome-Wide Association Study
- Plant Breeding
- Genotype
- Phenotype