Article
[Association of the Level of Serum Prolactin with Polymorphic Variants of the GRIN2A, GPM3, and GPM7 Genes in Patients with Schizophrenia Taking Conventional and Atypical Antipsychotics].
Molekuliarnaia biologiia - 1 Jan 2000
Tiguntsev V V, Gerasimova V I, Kornetova E G, Fedorenko O Yu, Kornetov A N, Goncharova A A, Poltavskaya E G, Boyko A S
Abstract excerpt
The dopamine, serotonin and glutamate systems are jointly involved in the pathogenesis and pharmacotherapy of schizophrenia. We formulated a hypothesis that polymorphic variants of the GRIN2A, GRM3, and GRM7 genes may be associated with the development of hyperprolactinemia in patients with schizophrenia taking conventional and atypical antipsychotics as basic treatment. 432 Caucasian patients diagnosed with...
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