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Article

Association of ANKK1 polymorphism with antipsychotic-induced hyperprolactinemia.

Human psychopharmacology - 1 Jul 2020

Fedorenko Olga Yu, Paderina Diana Z, Loonen Anton J M, Pozhidaev Ivan V, Boiko Anastasiia S, Kornetova Elena G, Bokhan Nikolay A, Wilffert Bob, Ivanova Svetlana A

Abstract excerpt

OBJECTIVE: Schizophrenia is a severe highly heritable mental disorder. Genetic polymorphisms of dopaminergic pathways are related to pathogenesis of drug response. Hyperprolactinemia (HPRL), a common adverse effect of antipsychotics, is attributed to blockade of dopamine D2 receptors. Ankyrin Repeat and Kinase Domain containing 1 (ANKK1) gene is closely related to Dopamine Receptor D2 type (DRD2) gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32383805
DOI: 10.1002/hup.2737
PMCID: PMC7507142

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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