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Article

Identification of 5-hydroxytryptamine receptor gene polymorphisms modulating hyperprolactinaemia in antipsychotic drug-treated patients with schizophrenia.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Apr 2017

Ivanova Svetlana A, Osmanova Diana Z, Freidin Maxim B, Fedorenko Olga Yu, Boiko Anastasia S, Pozhidaev Ivan V, Semke Arkadiy V, Bokhan Nikolay A, Agarkov Alexey A, Wilffert Bob, Loonen Anton J M

Abstract excerpt

OBJECTIVES: Hyperprolactinaemia (HPRL) is a classical side effect of antipsychotic drugs primarily attributed to blockade of dopamine D2 subtype receptors in the pituitary gland. Although dopamine is considered the primary factor inhibiting prolactin release, the activity of prolactin-producing lactotrophs is also regulated by the secretagogues thyrotrophin releasing hormone, vasoactive intestinal polypeptide and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27654063
DOI: 10.1080/15622975.2016.1224926

Genes

HTR6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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