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Article

Quantification of spatial and phenotypic heterogeneity in an agent-based model of tumour-macrophage interactions.

PLoS computational biology - 1 Mar 2023

Bull Joshua A, Byrne Helen M

Abstract excerpt

We introduce a new spatial statistic, the weighted pair correlation function (wPCF). The wPCF extends the existing pair correlation function (PCF) and cross-PCF to describe spatial relationships between points marked with combinations of discrete and continuous labels. We validate its use through application to a new agent-based model (ABM) which simulates interactions between macrophages and tumour cells. These...

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Identifiers

PMID: 36972297
DOI: 10.1371/journal.pcbi.1010994
PMCID: PMC10079237

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