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Article

Off-target effects in CRISPR/Cas9 gene editing

9 Mar 2023

Abstract excerpt

Gene editing stands for the methods to precisely make changes to a specific nucleic acid sequence. With the recent development of the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system, gene editing has become efficient, convenient and programmable, leading to promising translational studies and clinical trials for both genetic and non-genetic diseases. A major concern in the...

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PMID: 36970624
DOI: 10.3389/fbioe.2023.1143157

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