Article
CD27+ microparticle interactions and immunoregulation of CD4+ T lymphocytes.
Frontiers in immunology - 1 Jan 2023
Cagnet Léonie, Neyrinck-Leglantier Déborah, Tamagne Marie, Berradhia Lylia, Khelfa Mehdi, Cleophax Sabine, Pirenne France, Vingert Benoît
Abstract excerpt
Introduction: Aplasia and hematological malignancies are treated with platelet transfusions, which can have major immunomodulatory effects. Platelet concentrates (PCs) contain many immunomodulatory elements, including the platelets themselves, residual leukocytes, extracellular vesicles, such as microparticles (MPs), cytokines and other soluble elements. Two of these components, MPs and a soluble form of CD27...
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